ETHYL N-(DIPHENYLMETHYLENE)GLYCINATE AS ANIONIC GLYCINE EQUIVALENT - TRANSITION-METAL MEDIATED PREPARATION OF BICYCLIC AND TRICYCLIC ALPHA,ALPHA-DISUBSTITUTED ALPHA-AMINO-ACIDS AND DERIVATIVES

Authors
MORENOMANAS M PLEIXATS R ROGLANS A
Citation
M. Morenomanas et al., ETHYL N-(DIPHENYLMETHYLENE)GLYCINATE AS ANIONIC GLYCINE EQUIVALENT - TRANSITION-METAL MEDIATED PREPARATION OF BICYCLIC AND TRICYCLIC ALPHA,ALPHA-DISUBSTITUTED ALPHA-AMINO-ACIDS AND DERIVATIVES, Liebigs Annalen, (10), 1995, pp. 1807-1814
Citations number
44
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen → ACNP
ISSN journal
09473440
Issue
10
Year of publication
1995
Pages
1807 - 1814
Database
ISI
SICI code
0947-3440(1995):10<1807:ENAAGE>2.0.ZU;2-U
Abstract
Synthetic approaches to bicyclic and tricyclic alpha,alpha-disubstitut ed alpha-amino acids and derivatives 6, 8, 10, 12, 13, 21, 22, 23, 24, 28, 30, and 31 are presented. Methyl acetoacetate, ethyl nitroacetate , and ethyl N-(diphenylmethylene)glycinate are compared as anionic gly eine equivalents. Palladium-induced reductive couplings, Diels-Alder a nd Pauson-Khand reactions are used in the cyclisation steps.