A case of multiple eccrine spiradenomata is reported. One of the tumou
rs was histopathologically associated with dermal cylindroma, and immu
nohistochemical studies showed that the cylindroma cells differentiate
towards the secreting portion of the eccrine sweat gland. The relatio
nship among multiple eccrine spiradenomata, dermal cylindroma and mult
iple trichoepitheliomata is discussed.