USE OF PARTICLE-BEAM LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY FOR THE CHARACTERIZATION OF CHROMIUM AMINOCARBENE COMPLEXES

Chromium carbenes are used in organic synthesis as reagents to obtain molecules of biological interest, Zn this work a particle beam (PB) co upled liquid chromatography/mass spectrometry (LC/MS) system was used for the characterization of a mixture of chromium aminocarbene complex es. Three of them are new compounds. The separation of the examined co mplexes was performed using normal-phase chromatography. The acquisiti on of electron ionization, positive-ion and negative-ion chemical ioni zation mass spectra of the eluates was accomplished, The capability of the PB LC/MS technique in the on-line characterization of organometal lic compounds is highlighted. In addition, the fragmentation patterns of all the compounds considered are discussed. (C) 1997 by John Wiley & Sons, Ltd.