A NOVEL AND CONVENIENT CONVERSION OF CHLORINS TO PHYTOPORPHYRINS DURING THE MODIFICATION OF CHLOROPHYLL DERIVATIVES

Authors
MA LF DOLPHIN D
Citation
Lf. Ma et D. Dolphin, A NOVEL AND CONVENIENT CONVERSION OF CHLORINS TO PHYTOPORPHYRINS DURING THE MODIFICATION OF CHLOROPHYLL DERIVATIVES, Tetrahedron letters, 36(43), 1995, pp. 7791-7794
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
43
Year of publication
1995
Pages
7791 - 7794
Database
ISI
SICI code
0040-4039(1995)36:43<7791:ANACCO>2.0.ZU;2-H
Abstract
Chlorophyll derivatives 2a, 2b, 2c and 3 have been readily converted t o their corresponding phytoporphyrins 5a, 5b, 5c in excellent yields u sing benzoyl chloride in DMF. This method affords a new and efficient route to prepare monovinyl porphyrins which can be used as intermediat es for the further preparation of chlorophyll related petroporphyrins and regiochemically pure benzoporphyrin derivatives for use in photody namic therapy.