F. Cafieri et al., LONGAMIDE AND 3,7-DIMETHYLISOGUANINE, 2 NOVEL ALKALOIDS FROM THE MARINE SPONGE AGELAS-LONGISSIMA, Tetrahedron letters, 36(43), 1995, pp. 7893-7896
A purine derivative, 3,7-dimethylisoguanine (1), and a novel alkaloid
with the unusual pyrrolopiperazine nucleus, longamide (2), were isolat
ed from the sponge Agelas longissima, and their structures established
on the basis of spectroscopic data. In addition, 2 exhibited a mild a
ntibacterial activity.