G. Duan et Jy. Chen, KINETIC-ANALYSIS OF THE EFFECTS OF PRODUCTS REMOVAL ON THE HYDROLYSISOF PENICILLIN-G BY IMMOBILIZED PENICILLIN ACYLASE, Process biochemistry, 31(1), 1996, pp. 27-30
The effects of products removal on the hydrolysis of penicillin G by i
mmobilised penicillin acylase were studied by kinetic simulation. Anal
ysis of the substrate and products inhibition data from the literature
for this kinetically controlled reaction shows that the removal of ph
enylacetic acid (PAA) as produced in this reaction has little effect o
n the reaction rate.