ENZYMATIC REGIOSELECTIVE AND DIASTEREOSELECTIVE HYDROLYSIS OF PERACETYLATED GLYCEROL-BETA-GLUCOSIDES AND ERYTHRITOL-BETA-GLUCOSIDES

Authors
SORIENTE A DEROSA M TRINCONE A SODANO G
Citation
A. Soriente et al., ENZYMATIC REGIOSELECTIVE AND DIASTEREOSELECTIVE HYDROLYSIS OF PERACETYLATED GLYCEROL-BETA-GLUCOSIDES AND ERYTHRITOL-BETA-GLUCOSIDES, Bioorganic & medicinal chemistry letters, 5(20), 1995, pp. 2321-2324
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
20
Year of publication
1995
Pages
2321 - 2324
Database
ISI
SICI code
0960-894X(1995)5:20<2321:ERADHO>2.0.ZU;2-7
Abstract
Diastereomeric O-beta-glucosides at the primary carbons of glycerol an d erythritol have been subjected as their peracetates to enzymatic hyd rolysis by PFL. Only acetyl groups of the aglycones are hydrolyzed, th e diastereoselectivity being very high on the erythritol derivatives a nd fair on the glycerol derivatives. The chemical synthesis of 3R)-1-( O-beta-D-glucopyranosyl)-butane-2,3,4-triol heptaacetate is also repor ted.