PREPARATION AND PROPERTIES OF OLIGODEOXYNUCLEOTIDES CONTAINING 4-O-BUTYLTHYMINE, 2-FLUOROHYPOXANTHINE AND 5-AZACYTOSINE

Authors
AVINO A GARCIA RG MARQUEZ VE ERITJA R
Citation
A. Avino et al., PREPARATION AND PROPERTIES OF OLIGODEOXYNUCLEOTIDES CONTAINING 4-O-BUTYLTHYMINE, 2-FLUOROHYPOXANTHINE AND 5-AZACYTOSINE, Bioorganic & medicinal chemistry letters, 5(20), 1995, pp. 2331-2336
Citations number
45
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
20
Year of publication
1995
Pages
2331 - 2336
Database
ISI
SICI code
0960-894X(1995)5:20<2331:PAPOOC>2.0.ZU;2-P
Abstract
Oligonucleotides carrying the ammonia sensitive bases 4-O-butylthymine , 2-fluorohypoxanthine and 5-azacytosine have been prepared for the fi rst time using a special protocol that avoids the use of nucleophiles during the final deprotection.