6-BIS-[2-(3,4-DIHYDROXYBENZYL)PYRROLIDINYL]HEXANE, A POTENT, SELECTIVE, ORALLY-ACTIVE DOPAMINE ANALOG WITH HYPOTENSIVE AND DIURETIC ACTIVITY

Authors
FISHER LE ROSENKRANZ RP CLARK RD MUCHOWSKI JM MCCLELLAND DL MICHEL A CAROON JM GALEAZZI E EGLEN R WHITING RL
Citation
Le. Fisher et al., 6-BIS-[2-(3,4-DIHYDROXYBENZYL)PYRROLIDINYL]HEXANE, A POTENT, SELECTIVE, ORALLY-ACTIVE DOPAMINE ANALOG WITH HYPOTENSIVE AND DIURETIC ACTIVITY, Bioorganic & medicinal chemistry letters, 5(20), 1995, pp. 2371-2376
Citations number
34
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
20
Year of publication
1995
Pages
2371 - 2376
Database
ISI
SICI code
0960-894X(1995)5:20<2371:6APS>2.0.ZU;2-6
Abstract
The D-1 and D-2 affinities, in vivo femoral and renal vasodilatory eff ects, oral antihypertensive and diuretic effects and syntheses of sele cted dopamine congeners are described.