EPIDEMIC SPREAD OF PLASMID-MEDIATED TETRACYCLINE RESISTANT NEISSERIA-GONORRHOEAE IN ZAIRE

Authors
VANDYCK E LAGA M MANOKA AT BEHETS F PIOT P
Citation
E. Vandyck et al., EPIDEMIC SPREAD OF PLASMID-MEDIATED TETRACYCLINE RESISTANT NEISSERIA-GONORRHOEAE IN ZAIRE, International journal of STD & AIDS, 6(5), 1995, pp. 345-347
Citations number
NO
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
International journal of STD & AIDS → ACNP
ISSN journal
09564624
Volume
6
Issue
5
Year of publication
1995
Pages
345 - 347
Database
ISI
SICI code
0956-4624(1995)6:5<345:ESOPTR>2.0.ZU;2-Q
Abstract
A cohort of 650 prostitutes from Kinshasa, Zaire, was followed at mont hly intervals for sexually transmitted diseases as part of an HIV inte rvention project. Neisseria gonorrhoeae isolates, obtained during a pe riod of 30 months, were auxotyped, serotyped and tested for antimicrob ial susceptibility. Among 1085 gonococcal isolates tested, 725 (67%) p roduced beta-lactamase (PPNG) and 323 (30%) showed plasmid-mediated re sistance to tetracyline (TRNG). Over time, the prevalence of PPNG vari ed between 60 and 73%, while the level of TRNG increased from 11 to 45 %.