ERYTHROCYTE LACTATE-DEHYDROGENASE IN TYPE-1 DIABETES-MELLITUS

Authors
RIZVI SI
Citation
Si. Rizvi, ERYTHROCYTE LACTATE-DEHYDROGENASE IN TYPE-1 DIABETES-MELLITUS, National Academy Science Letters, 18(3-4), 1995, pp. 81-83
Citations number
NO
Categorie Soggetti
Multidisciplinary Sciences
Journal title
National Academy Science Letters → ACNP
ISSN journal
0250541X
Volume
18
Issue
3-4
Year of publication
1995
Pages
81 - 83
Database
ISI
SICI code
0250-541X(1995)18:3-4<81:ELITD>2.0.ZU;2-U
Abstract
The activity Of erythrocyte lactate dehydrogenase (LDH) was studied in normal individuals, type 1 diabetics and insulin treated diabetics. T he activity of LDH was found to be significantly increased in diabetic state, however, insulin treatment restored the activity to normal lev el. The increased LDH activity in diabetes compensates the demand for NAD+ by glyceraldehyde-3-phosphtate dehydrogenase, the activity of whi ch has also been found to be elevated in diabetes mellitus.