Purpose: Ocular lens, retina, and olfactory bulb exposure are common c
oncerns in contemporary radiotherapy practice. Methods to clinically l
ocalize soft tissue structures (i.e., lens and retina) are varied and
often imprecise. We hypothesized that eyelid markers constituted a bet
ter reference point than the commonly used lateral canthus marker for
lateral beam simulations, unless diagnostic computed tomography or ult
rasound examinations were available and/or used.Methods and Materials:
Sixty-six pre-Magnetic Resonance Image, normal, orbital computed tomo
graphy scans from adult patients were used to measure (a) sagittal dis
tances from eyelid to posterior lens surface, from lateral canthus to
posterior lens surface and to the globe's posterior pole, (b) supero-i
nferior distances in the lateral projection from the lens to the cribr
iform plate, and (c) common dimensions to establish internal validity
of the measurements. Results: The eyelid to lens and retina topography
is individually more constant than that from the canthus. There is li
ttle if any supero-inferior separation between the lens and the cribri
form plate lateral projections. Conclusions: The lateral canthus does
not specify lens or retina locations. Eyelid markers of known size pro
vide more accurate anatomical information. Lateral beam ocular globe s
hielding has to be individualized. Lens shielding is questionable if t
he olfactory bulb needs to be irradiated by a lateral beam.