F. Veglio et al., ASSESSMENT OF RENAL RESISTANCE INDEX AFTER CAPTOPRIL TEST BY DOPPLER IN ESSENTIAL AND RENOVASCULAR HYPERTENSION, Kidney international, 48(5), 1995, pp. 1611-1616
Ultrasonic duplex scanning has been validated as a noninvasive method
to evaluate the kidney arteries and hemodynamic characteristics of ren
al blood flow in patients with renal artery stenosis. The purpose of o
ur study was to assess the changes in renal vascular impedance in 22 p
atients with renovascular hypertension, as compared with 45 essential
hypertensives and 15 normotensives, by using the Doppler parameter res
istance index (RI) before and after a captopril oral test. After the c
aptopril test the Delta RI decreased significantly in the stenotic art
ery (P < 0.05). Univariate analysis showed that PRA values after capto
pril correlated inversely with the changes of RI only in the stenotic
artery (P < 0.05). Thus, our findings suggest that the application of
the captopril test to renal echo-Doppler may represent a feasible, non
invasive, and inexpensively useful tool in the screening studies aimed
at diagnosing renovascular hypertension.