TRANSLOCATION T(6-9-8)(P23-Q34-Q22) IN AC UTE MYELOBLASTIC-LEUKEMIA -CONTRIBUTION OF FLUORESCENCE IN-SITU HYBRIDIZATION

Authors
VANDENAKKER J PEROT C PORTNOI MF PHILIZOT L DUPONT JM LAPORTE JP TAILLEMITE JL
Citation
J. Vandenakker et al., TRANSLOCATION T(6-9-8)(P23-Q34-Q22) IN AC UTE MYELOBLASTIC-LEUKEMIA -CONTRIBUTION OF FLUORESCENCE IN-SITU HYBRIDIZATION, Annales de genetique, 38(3), 1995, pp. 168-171
Citations number
21
Categorie Soggetti
Genetics & Heredity
Journal title
Annales de genetique → ACNP
ISSN journal
00033995
Volume
38
Issue
3
Year of publication
1995
Pages
168 - 171
Database
ISI
SICI code
0003-3995(1995)38:3<168:TTIAUM>2.0.ZU;2-H
Abstract
A complex translocation involving chromosome 6, 8 and 9 [t(6;9;8)(p23; q34;q22)] associated with other structural and numerical abnormalities was observed on bone marrow karyotype of a woman suffering with acute myeloblastic leukemia (AML 2). Fluorescence in situ hybridization agr eed with the conventional cytogenetic interpretation by showing that a part of chromosome 6 short arm was inserted on the rearranged chromos ome 9 resulting in the t (6;9) usually encountered in AML.