M. Ueki et al., VISUAL FINDINGS AND HISTOLOGIC DIAGNOSIS OF PELVIC ENDOMETRIOSIS UNDER LAPAROSCOPY AND LAPAROTOMY, International journal of fertility and menopausal studies, 40(5), 1995, pp. 248-253
Objective-To assess the diagnostic value of visual findings in the dia
gnosis of endometriosis from the histological point of view. Study Des
ign-212 specimens from 107 patients with benign (74.8%) or malignant (
25.2%) disease were obtained by biopsy or resection under laparoscopy
(65 patients) or laparotomy (42 patients). Ages ranged from 19 to 62 (
mean age 36.4). Visual findings were classified according to the crite
ria established by the Endometriosis Committee of the Japan Society of
Obstetrics and Gynecology in 1993. Specimens were stained with hemato
xylin-eosin, and 15 cases with periodic acid-Schiff stain or silver im
pregnation stain. Results-Among pigmented lesions, endometriosis was f
ound in 73.0% of specimens from the pelvic peritoneum and in 56.4% of
those from the ovaries. Blueberry spots in the pelvic peritoneum as we
ll as ovarian chocolate cysts showed the highest positive rate. In the
presence of multiple or complex pigmented lesions of the pelvic area,
the rate was still higher (88.6%). Those rates were due to our inclus
ion of inaccurate and incomplete biopsy specimens. Endometriosis of no
npigmented lesions was found in only 11 patients (12.0%) who also had
pigmented lesions and/or adenomyosis. Conclusion-The laparoscopic diag
nosis of endometriosis can be made only when multiple complex pigmente
d lesions are observed, but, otherwise, histopathological confirmation
is necessary.