ANTI-PURIFIED PROTEIN DERIVATIVE CELL-ENZYME-LINKED IMMUNOSORBENT-ASSAY, A SENSITIVE METHOD FOR EARLY DIAGNOSIS OF TUBERCULOUS MENINGITIS

Authors
Citation
Sm. Baig, ANTI-PURIFIED PROTEIN DERIVATIVE CELL-ENZYME-LINKED IMMUNOSORBENT-ASSAY, A SENSITIVE METHOD FOR EARLY DIAGNOSIS OF TUBERCULOUS MENINGITIS, Journal of clinical microbiology, 33(11), 1995, pp. 3040-3041
Citations number
15
Categorie Soggetti
Microbiology
ISSN journal
00951137
Volume
33
Issue
11
Year of publication
1995
Pages
3040 - 3041
Database
ISI
SICI code
0095-1137(1995)33:11<3040:APDCI>2.0.ZU;2-Z
Abstract
A cell-enzyme-linked immunosorbent assay method was developed for the diagnosis of tuberculous meningitis by determining anti-purified prote in derivative antibody production by cells derived from cerebrospinal fluid and peripheral blood. Of 20 patients with clinical histories and CSF findings suggestive of tuberculous meningitis, 18 showed high pro duction of anti-purified protein derivative immunoglobulin antibody fr om CSF-derived lymphocytes, while none of the controls showed such res ponse.