COMPARISON OF MAGNETOENCEPHALOGRAPHY, FUNCTIONAL MRI, AND MOTOR EVOKED-POTENTIALS IN THE LOCALIZATION OF THE SENSORY-MOTOR CORTEX

To clarify the topographical relationship between peri-Rolandic lesion s and the central sulcus, we carried out presurgical functional mappin g by using magnetoencephalography (MEG), functional magnetic resonance imaging (f-MRI), and motor evoked potentials (MEPs) on 5 patients. Th e sensory cortex was identified by somatosensory evoked magnetic field s using MEG (magnetic source imaging (MSD)). The motor area of the han d region was identified using I-MRI, during a hand squeezing task. In addition, transcranial magnetic stimulation localized the hand motor a rea on the scalp, which was mapped onto the MRI. In all cases, the sen sory cortical vein or the lack of any functional activation in the are a of peri-lesional edema. MEPs were also unable to localize the entire motor strip. Therefore, at present, MSI is considered to be the most reliable method to localize peri-Rolandic lesions. [Neurol Res 1995; 1 7: 361-367] cortical vein or the lack of any functional activation in the area of peri-lesional edema. MEPs were also unable to localize the entire motor strip. Therefore, at present, MSI is considered to be th e most reliable method to localize peri-Rolandic lesions.