Jw. Griffith et al., EXPERIMENTAL PNEUMONIA VIRUS OF MICE INFECTION OF GUINEAPIGS SPONTANEOUSLY INFECTED WITH BORDETELLA-BRONCHISEPTICA, Laboratory animals, 31(1), 1997, pp. 52-57
Guineapigs that were intranasally inoculated with pneumonia virus of m
ice (PVM) seroconverted to PVM by 11 days post-infection. During the c
ourse of study (2-60 days postinfection) no gross or histologic lesion
s were identified within the lungs that could be attributed to PVM inf
ection. Mild rhinitis and tracheitis were found in most animals and ac
ute purulent bronchopneumonia in two animals which may have resulted f
rom spontaneous subclinical Bordetella bronchiseptica infection. Viral
and bacterial respiratory diseases of the guineapig are briefly revie
wed.