ENDOMETRIAL STAGE-I CARCINOMA TREATED WITH SURGERY AND ADJUVANT IRRADIATION - A RETROSPECTIVE ANALYSIS

Aims and background: Data from the literature show that the incidence of Pelvic recurrences in poor prognosis endometrial carcinoma is signi ficantly reduced by combined surgery and radiotherapy compared to surg ery alone. Methods: in this paper we analyze the results of the combin ed treatment surgery and adjuvant irradiation in patients with endomet rial carcinoma with regard to survival, site of progression, and toxic ity. the surgical treatment consisted of total abdominal hysterectomy and bilateral salpingo-oophorectomy in 40 patients. Pelvic and para-ao rtic node dissection was performed in 19 patients and lymph node sampl ing in 5. Results: Overall 5-year survival was 85%. One patient had lo cal failure, and 5 patients with local control of disease had distant metastases. toxicity was mild and transient. Conclusions: Our experien ce confirms the data of the literature. postoperative irradiation is a safe and well-tolerated treatment that can achieve a good local contr ol in high risk, stage I, endometrial carcinoma. the control of distan t metastases remains an open question.