EVALUATION OF CYTOKINE PRODUCTION IN LEPR OSY PATIENTS

Citation
S. Fink et al., EVALUATION OF CYTOKINE PRODUCTION IN LEPR OSY PATIENTS, Medicina, 56(6), 1996, pp. 705-708
Citations number
13
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
00257680
Volume
56
Issue
6
Year of publication
1996
Pages
705 - 708
Database
ISI
SICI code
0025-7680(1996)56:6<705:EOCPIL>2.0.ZU;2-J
Abstract
The aim of the present study was to evaluate the cytokine production b y peripheral blood mononuclear cells (PBMC) of leprosy patients when t he cells were stimulated in culture by ConA, PPD or M.leprae. We measu red IL-2, IL-4, IFN-gamma and IL-6 in cell-free supernatants by enzyme linked immunoassays. Our results do not suggest a clear association o f a clinical form of leprosy with either Th1 or Th2 cytokine secretion profile in PBMC of leprosy patients.