The aim of the present study was to evaluate the cytokine production b
y peripheral blood mononuclear cells (PBMC) of leprosy patients when t
he cells were stimulated in culture by ConA, PPD or M.leprae. We measu
red IL-2, IL-4, IFN-gamma and IL-6 in cell-free supernatants by enzyme
linked immunoassays. Our results do not suggest a clear association o
f a clinical form of leprosy with either Th1 or Th2 cytokine secretion
profile in PBMC of leprosy patients.