In March 1995 the first case of a familiar outbreak of Hantavirus pulm
onary syndrome (HPS) was notified in El Bolson, in the South of Argent
ina. Until December 15, 1996, a total of 77 cases of HPS had been noti
fied with 48% mortality, distributed in three geographical areas of th
e country, South, North and Center. During 1996, of the 19 cases from
El Bolson, three were local physicians, one of whom -during the prodro
me of her illness- travelled to Buenos Aires to be attended. In the ho
spital, two of the physicians who assisted her, developed HPS 27 and 2
8 days after the first contact. These data suggest for the first time
the possibility of interhuman transmission of the Hantavirus responsib
le for the pulmonary syndrome.