SYNTHESIS OF FLUORO-VERATRALDEHYDES AND POLYFLUORO-VERATRALDEHYDES BYELECTROPHILIC FLUORINATION

Authors
NIE JY KIRK KL
Citation
Jy. Nie et Kl. Kirk, SYNTHESIS OF FLUORO-VERATRALDEHYDES AND POLYFLUORO-VERATRALDEHYDES BYELECTROPHILIC FLUORINATION, Journal of fluorine chemistry, 74(2), 1995, pp. 297-301
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of fluorine chemistry → ACNP
ISSN journal
00221139
Volume
74
Issue
2
Year of publication
1995
Pages
297 - 301
Database
ISI
SICI code
0022-1139(1995)74:2<297:SOFAPB>2.0.ZU;2-D
Abstract
Lithiation of oxazolines derived from fluorinated veratric acid, follo wed by electrophilic fluorination and subsequent reductive oxazoline c leavage, provides a convenient route to di- and tri-fluoroveratraldehy des. Similarly, 4-fluoroveratrol was converted by lithiation and fluor ination to 3,4-difluoroveratrol, which can be used to prepare 5,6-difl uoroveratraldehyde.