Point-of-care testing is a rapidly expanding trend. This review discus
ses some of the issues driving the development of this new approach to
laboratory testing, assesses the factors appropriate in introducing a
nd managing point-of-care testing, and directs attention to realistica
lly assessing the potential for cost-effectiveness analysis. Although
considered optimal, formal cost-effective analysis is limited. A comme
ntary on the published literature of the field is presented. Observati
ons are offered on the inadequacies of published studies that purport
to describe this application. As an alternative, a more general assess
ment of the economic effect of point-of-care testing in the general co
ntext of the laboratory mission is recommended. Suggested guidelines a
re included.