COLORECTAL-CANCER - SURGICAL PROPHYLAXIS AND CHEMOPREVENTION

Authors
NUGENT KP
Citation
Kp. Nugent, COLORECTAL-CANCER - SURGICAL PROPHYLAXIS AND CHEMOPREVENTION, Annals of the Royal College of Surgeons of England, 77(5), 1995, pp. 372-376
Citations number
55
Categorie Soggetti
Surgery
Journal title
Annals of the Royal College of Surgeons of England → ACNP
ISSN journal
00358843
Volume
77
Issue
5
Year of publication
1995
Pages
372 - 376
Database
ISI
SICI code
0035-8843(1995)77:5<372:C-SPAC>2.0.ZU;2-R
Abstract
Attempts at improving outcome from colorectal cancer have recently foc used on prevention. This paper describes how both surgical and chemoth erapeutic intervention can cause a fall in cell proliferation, polyp r egression and a decline in rectal cancer risk in patients with familia l adenomatous polyposis. Other patients at high risk of colorectal can cer, or of cancers in other sites, may also have their risks modified by pharmacological intervention.