Actinomycosis osteitis is rare. We report a case of actinomycosis oste
itis of skull basis in immunocompetent 38 years old male. Infection wa
s developed from chronic otitis. Diagnosis was difficult and establish
ed after surgical biopsy. Adequate surgical procedure and prolonged an
tibiotic therapy with Trimethoprim-Sulfamethoxazole were efficent.