UTILIZATION OF A SELF-ASSEMBLED PEPTIDE MONOLAYER FOR AN IMPEDIMETRICIMMUNOSENSOR

Authors
KNICHEL M HEIDUSCHKA P BECK W JUNG G GOPEL W
Citation
M. Knichel et al., UTILIZATION OF A SELF-ASSEMBLED PEPTIDE MONOLAYER FOR AN IMPEDIMETRICIMMUNOSENSOR, Sensors and actuators. B, Chemical, 28(2), 1995, pp. 85-94
Citations number
40
Categorie Soggetti
Engineering, Eletrical & Electronic","Instument & Instrumentation
Journal title
Sensors and actuators. B, Chemical → ACNP
ISSN journal
09254005
Volume
28
Issue
2
Year of publication
1995
Pages
85 - 94
Database
ISI
SICI code
0925-4005(1995)28:2<85:UOASPM>2.0.ZU;2-2
Abstract
Layers of a thiol-containing synthetic peptide constituting an epitope of the foot-and-mouth-disease virus are formed on gold electrodes via self-assembly. The immunological reactivity of the modified electrode s towards a monoclonal antibody is confirmed by performing an ELISA. T he binding of a specific antibody to epitope-modified gold electrodes can be detected by measuring changes of the Faradaic impedance.