THE ENDOTHELIN ET(A) RECEPTOR EXISTS IN THE CAUDAL SOLITARY TRACT NUCLEUS OF THE RAT-BRAIN

Authors
SHIBATA S NIWA M HIMENO A GANA NG SHIGEMATSU K MATSUMOTO M YAMASHITA K SUMIKAWA K TANIYAMA K
Citation
S. Shibata et al., THE ENDOTHELIN ET(A) RECEPTOR EXISTS IN THE CAUDAL SOLITARY TRACT NUCLEUS OF THE RAT-BRAIN, Cellular and molecular neurobiology, 17(1), 1997, pp. 151-156
Citations number
14
Categorie Soggetti
Neurosciences,"Cell Biology",Biology
Journal title
Cellular and molecular neurobiology → ACNP
ISSN journal
02724340
Volume
17
Issue
1
Year of publication
1997
Pages
151 - 156
Database
ISI
SICI code
0272-4340(1997)17:1<151:TEEREI>2.0.ZU;2-W
Abstract
1, The receptor autoradiographic method done on the rat lower brain st em and cerebellum plus I-125-endothelin-1, BQ-123, an antagonist for t he endothelin ET(A) receptor, and sarafotoxin S6c, an agonist for the ET(B) receptor, revealed minute amounts of the ET(A) receptor coexisti ng with the ET(B) receptor in the caudal solitary tract nucleus of the rat lower brain stem. 2. The ET(B) receptor is present predominantly in other parts of the lower brain stem. 3, Knowledge of the heterogene ous distribution of the central endothelin receptor subtypes aids in u nderstanding the neurophysiology of endothelins.