We have observed that hydrosalpinx develops in some patients undergoin
g ovulation induction as part of in vitro fertilization-embryo transfe
r and gamete intrafallopian transfer programs. Increased tubal secreti
ons due to multihormonal stimulation causes a blocked tube to distend
by the time of oocyte harvest. In a subset of women; hydrosalpinx was
not identified on initial pelvic sonograms. Hydrosalpinx became appare
nt during serial sonography to monitor follicular development. We perf
ormed a retrospective chart review of these eases in order to confirm
this finding with hysterosalpingography or laparoscopy. Nine of 316 wo
men developed unilateral (eight cases) or bilateral hydrosalpinx (one
case) during stimulation. Recognition of this sonographic finding is i
mportant to the referring physician because it has important therapeut
ic and outcome implications.