Ld. Montgomery et al., MASSIVE FETOMATERNAL HEMORRHAGE TREATED WITH SERIAL COMBINED INTRAVASCULAR AND INTRAPERITONEAL FETAL TRANSFUSIONS, American journal of obstetrics and gynecology, 173(1), 1995, pp. 234-235
One of the many causes of fetal hydrops is fetomaternal hemorrhage. Th
is report presents a pregnancy with fetomaternal hemorrhage that was t
reated with serial combined intravascular and intraperitoneal fetal tr
ansfusions, resulting in a good outcome. A 26-year-old woman seen for
ultrasonographic evaluation was found to have a fetus with hydrops fet
alis. Fetal blood sampling demonstrated severe fetal anemia (hematocri
t 16.4%). The initial Kleihauer-Betke test result on maternal blood wa
s 6% fetal cells. The fetus was transfused five times over a 24-day pe
riod by means of a combined intravascular and intraperitoneal route. T
he fetus also received one platelet transfusion for thrombocytopenia.
The pregnancy resulted in a good fetal outcome without the need for po
stpartum transfusion. This case represents successful treatment of fet
al anemia and nonimmune hydrops with a serial combined intravascular a
nd intraperitoneal transfusion technique.