This report presents two probable cases of Lyme arthritis triggered by
athletic activity or trauma. One patient had ankle swelling after he
began a jogging program, and a second had knee swelling that followed
a twisting injury. The report describes the three stages of the illnes
s and presents diagnostic lab tests and the therapies used. Polymerase
chain reaction (PCR) testing of the synovial fluid can be useful in d
iagnosing active Lyme arthritis, but it may yield a false-negative res
ult when there has been recent remission of the arthritis.