Go-occurrence of psychotic and obsessive-compulsive symptoms was first
reported nearly 70 years ago. This paper reviews published reports fr
om two perspectives: psychotic disorders with obsessive-compulsive sym
ptoms and obsessive-compulsive disorder (OCD) with psychotic symptoms.
Older investigations reported a low rate of comorbidity between these
two disorders, but more-recent studies, in which systematic diagnosti
c criteria have been used, have suggested that the rate of co-occurren
ce of symptoms is higher than was previously thought. The difficulty i
n diagnosing patients with obsessive-compulsive and psychotic symptoms
is reviewed, and the importance of this distinction for treatment and
prognosis is discussed. Although the comorbid diagnosis of schizophre
nia and OCD, or of OCD and psychotic features, seems to portend a wors
e prognosis than for either illness alone, the available data suggest
that some patients with schizophrenia and OC symptoms may improve with
traditional antiobsessional treatment.