ISOCHROMOSOME 6P AND DELETION OF 6Q CHARACTERIZE 2 RELATED CYTOGENETIC CLONES IN A PATIENT WITH IMMUNOBLASTIC LYMPHOMA

Authors
SCARAVAGLIO P SAGLIO G GEUNA M PALESTRO G GUGLIELMELLI T REGECAMBRIN G
Citation
P. Scaravaglio et al., ISOCHROMOSOME 6P AND DELETION OF 6Q CHARACTERIZE 2 RELATED CYTOGENETIC CLONES IN A PATIENT WITH IMMUNOBLASTIC LYMPHOMA, Cancer genetics and cytogenetics, 81(2), 1995, pp. 179-181
Citations number
6
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
81
Issue
2
Year of publication
1995
Pages
179 - 181
Database
ISI
SICI code
0165-4608(1995)81:2<179:I6ADO6>2.0.ZU;2-0
Abstract
In a case of immunoblastic lymphoma we observed the presence of either a deletion of the long arm of chromosome 6 or of an isochromosome, i( 6p), which occurred alternatively in metaphase cells. This suggests a selective pressure for loss of heterozygosity of genes located on 6q a nd is in accordance with the hypothesis that one or more tumor suppres sor genes might be located on the long arm chromosome 6.