The dynamics of a fed-batch reactor was studied using the detailed fir
st principle model of the system. The conditions of reaction runaway,
the typical sources of hazardous operation in fed-batch techniques are
determined. Considering these conditions a model-based control scheme
is proposed to ensure robustness. When the stability criterion predic
ts that the range of operation is safe the cooling is set to its maxim
um and the temperature is controlled by the reactant feed. Otherwise t
he reactant feed is stopped and the flow rate of the cooling medium is
the control variable.