S. Nazari et al., EXPANDABLE PROSTHESIS FOR SUTURELESS ANASTOMOSIS IN THORACIC AORTA PROSTHETIC SUBSTITUTION, European journal of cardio-thoracic surgery, 10(11), 1996, pp. 1003-1009
Objective. Most complications of descending aorta prosthetic substitut
ion seem mainly to be related directly (ischemia to distal organs, i.e
. liver, kidney, spinal cord) or indirectly (extracorporeal circulatio
n or shunts and systemic heparinization complications) to the duration
of blood flow interruption. The purpose of this study is to report th
e results of animal experimentation of a new device for sutureless pro
sthetic substitution of the descending thoracic aorta, with a very sho
rt crossclamping phase. Methods. The device consists of expandable loo
ps of stainless steel wires, sewn to the proximal end of a Dacron pros
thesis. The stainless steel wire loops can be expanded and tightened b
y activating a removable guide in such a way that the prosthesis varie
s its diameter, while maintaining a regular cylindrical shape. The dev
ice was prepared in two different configurations, one for long segment
s (expandable prosthesis end) and the other to be used for very short
segments or as an anastomotic ring between prosthetic or vascular stum
ps (quick anastomotic ring). The expandable prosthesis end was tested
in swine experiments by performing the prosthetic substitution of the
first 10 cm of descending cross-clamped aorta, the prosthesis being fi
xed with the device both at the proximal and the distal ends (six expe
riments). All animals survived the procedure, that was accomplished wi
th a very short crossclamping time. The quick anastomotic ring was use
d to anastomose two prosthesis ends, at the middle of the prosthetic s
egment used for descending aorta substitution (two swine), to perform
the distal anastomosis in the same model of descending aorta substitut
ion (one swine) and simply to re-anastomose a subtotally transected de
scending aorta (one swine). Results. The present experience proved the
reliability of the device to carry out a sutureless, accurate, simple
and quick anastomosis. Its advantage over an intraluminal ringed pros
thesis is much easier insertion of the retracted wired end into the va
scular stumps, thus allowing for a prosthetic diameter appropriate to
the substituted vessel. Conclusions. The reduced crossclamping feature
of the device would suggest its use mainly in thoracic aorta prosthet
ic substitution for the prevention of ischemic damage to distal organs
; it can also be used to advantage wherever an end-to-end vascular or
prosthetic anastomosis is indicated, providing an accurate, stented an
astomosis.