ALLYLBORATION OF ALPHA-AMINO KETONES

A series of unsaturated alpha-amino alcohols were prepared via the all ylboration of the corresponding N-protected alpha-amino ketones. The r eactions are stereoselective, producing the syn isomers. The diastereo selectivity is not dramatically effected by the electronic nature of t he N-protecting group or the reaction temperature but is dependent on the steric requirements of the N-protecting group and the solvent syst em.