Rh. Davis et al., ALOE VERA, HYDROCORTISONE, AND STEROL INFLUENCE ON WOUND TENSILE-STRENGTH AND ANTI-INFLAMMATION, Journal of the American Podiatric Medical Association, 84(12), 1994, pp. 614-621
Aloe vera at doses of Inn and 300 mg/kg daily for 4 days blocked the w
ound heating suppression of hydrocortisone acetate up to 100% using th
e wound tensile strength assay. This response was because of the growt
h factors present in A. vera masking the wound healing inhibitors such
as sterols and certain amino acids. The sterols showed good anti-infl
ammatory activity (-36%) in reducing the croton oil-induced ear swelli
ng. This activity displayed a dose-response relationship.