Dc. Abramson, SUDDEN UNEXPECTED SNEEZING DURING THE INSERTION OF PERIBULBAR BLOCK UNDER PROPOFOL SEDATION, Canadian journal of anaesthesia, 42(8), 1995, pp. 740-743
The author presents a case report where, following propofol sedation f
or a peribulbar block, sneezing was induced once the local anaesthetic
needle was placed in the orbital cavity. The physiology of sneezing i
s discussed as well as the pathophysiology of the ACHOO (Autosomal Dom
inant Compelling Helio-Ophthalmic Outburst) syndrome, an autosomal dom
inant condition, present in approximately 25% of the population, where
sneezing is provoked upon exposure to bright light. It is suggested t
hat the anaesthesia induced by propofol may have sensitized patients w
ith this condition to sneeze, since there appeared to be no other exci
tatory sequelae which have previously been described with propofol.