Many cognitive functions have been shown to deteriorate with age. Beca
use of the importance of the menopause as a milestone in the life cycl
es of women, we examined whether the aging-over-time process in some c
ognitive functions differs between women of reproductive age and postm
enopausal women. It is demonstrated here that in some cognitive tests,
including driving simulation, reaction time and some visuospatial tes
ts, there is a significant acceleration in deterioration of functionin
g following menopause. It is suggested that this acceleration might be
associated with the lack of gonadal hormones or other reproduction-re
lated factors which may play a protective role against age-related det
erioration in some cognitive functions in women.