Cr. Ekechukwu et al., SELECTION AND CHARACTERIZATION OF ASPARTOKINASE FEEDBACK-INSENSITIVE MUTANTS OF AZOTOBACTER-VINELANDII, Applied and environmental microbiology, 61(8), 1995, pp. 3189-3191
Aspartokinase feedback-insensitive mutants of Azotobacter vinelandii w
ere selected as resistant to L-threonine, beta-hydroxynorvaline, or S-
(2-aminoethyl)-L-cysteine. L-Threonine-resistant strains were classifi
ed into three groups based on their ability to transport L threonine a
nd their growth response to O-methylthreonine and beta-hydroxynorvalin
e. Most of the mutants were transport defective; however, some were de
sensitized to feedback regulation.