Rd. Cohn et al., MALIGNANT RHABDOID TUMOR OF THE BRAIN AND KIDNEY IN A CHILD - CLINICAL AND PATHOLOGICAL FEATURES, Pediatric neurology, 13(1), 1995, pp. 65-68
Malignant rhabdoid tumor (MRT) is most frequently found in the kidney,
but can occur in other tissues including the brain, The simultaneous
appearance of MRT in the brain and kidney has rarely been described. W
e report the first fully described case of simultaneous appearance of
MRT in the kidney and cerebellum of an 8-month-old boy, Cytoplasmic in
clusion-like masses, representing aggregates of intermediate filaments
, positively stained by Vimentin and by epithelial membrane antigen, w
ere abundant in the kidney tumor but rare in the cerebellar tumor, sug
gesting that this often-described characteristic of kidney MRT can be
an infrequently observed feature of brain MRT, which consequently may
be thought to represent another type of tumor.