IN-HOSPITAL OUTCOME OF PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTYFOR LONG LESIONS AND DIFFUSE CORONARY-ARTERY DISEASE

We performed coronary angioplasty on 151 long or diffuse lesions (120 long and 31 diffuse) in 141 patients (86% male, mean age 50 +/- 9 year s), Long lesions were defined as lesions 11-20 mm in length and diffus e lesions as lesions longer than 20 mm, or three or more lesions in th e same vessel. One or more adverse morphologic features were present i n 131 (93%) lesions. Long balloons were used in 44%, significantly mor e often for diffuse disease (long lesions 39% and diffuse disease 64%; P = 0.004), Newer devices including the rotational atherectomy device (9 lesions), stents and perfusion balloons were employed in 18 (12%) lesions, more often for diffuse lesions (long lesions 8% vs, diffuse l esions 26%; P = 0.017). Lesion severity was comparable in the two grou ps (long lesions: 88 +/- 7%; diffuse lesions: 88 +/- 8%), but diffuse lesions were associated with significantly higher residual stenosis (l ong lesions: 6 +/- 8%; diffuse lesions: 12 +/- 13%, P = 0.01), Major c omplications occurred in five (3.5%) patients, including one death (0. 7% mortality). The angiographic and clinical success rates for all pat ients were 99% and 96%, respectively, and were comparable for long and diffuse lesions. Judicious case selection and the use of long balloon s and newer interventional devices permit coronary angioplasty for lon g lesions and diffuse disease with excellent success and a low risk of complications. Diffuse lesions are associated with more frequent use of long balloons and newer devices, especially rotational atherectomy and slightly higher residual stenosis as compared to long lesions. (C) 1995 Wiley-Liss, Inc.