G. Ambrosetto et L. Antonini, ANTERIOR CORPUS CALLOSOTOMY - EFFECTS IN A PATIENT WITH CONGENITAL BILATERAL PERISYLVIAN SYNDROME AND OROMOTOR SEIZURES, Italian journal of neurological sciences, 16(5), 1995, pp. 311-314
Anterior corpus callosotomy was performed in a patient with pseudobulb
ar palsy, mild mental retardation and intractable epilepsy related to
congenital bilateral perisylvian cortical dysplasia. Before surgery, s
he had daily atonic drop attacks, rare and mainly sleep-related oromot
or seizures, and multifocal and diffuse paroxysmal EEG discharges; aft
er callosotomy, less abrupt atonic drop attacks recurred monthly and t
he EEG epileptiform abnormalities disappeared. Video-EEG sleep recordi
ngs revealed the clinically unsuspected serial recurrence of oromotor
seizures, probably related to the clinically observed aggravation of d
ysarthria. New surgical techniques, in addition or alternative to call
osotomy, should be developed in order to avoid or reduce the risk of a
ggravating some types of partial seizures in patients with bilateral c
ortical displastic lesions, intractable epilepsy and epileptic falls.