PAROXYSMAL DYSTONIA AND PAROXYSMAL TREMOR IN A YOUNG PATIENT WITH MULTIPLE-SCLEROSIS

A 16-year-old patient with multiple sclerosis (MS) showed paroxysmal m ovement disorders during a recurrence of the disease. The paroxysms to ok the form ot brief unilateral dystonic posturings of the right body suggestive of paroxysmal dystonia (PD); they completely receded with a cetazolamide, A single episode of a high amplitude, rythmic slow and c oarse generalized tremor present at rest and increasing with movement, particularly involving the head in a no-no movement, occurred soon af ter recovery from PD and lasted three hours, The present report provid es evidence that MS has to be considered in the diagnostic approach to symptomatic childhood PD and underlines the efficacy of acetazolamide in the treatment of PD attacks. It also describes a rare paroxysmal m ovement disorder, defined as paroxysmal dystonic tremor, that can be c onsidered as falling within the spectrum of PD.