EFFECT OF NOVEL AROMATIC DERIVATIVE OF GABA ON LIPID-PEROXIDATION IN CHRONICALLY MORPHINIZED RATS

Authors
LURIE E SOLOVIOVA A ALYABIEVA T KAPLUN A PANCHENKO L SHVETS V
Citation
E. Lurie et al., EFFECT OF NOVEL AROMATIC DERIVATIVE OF GABA ON LIPID-PEROXIDATION IN CHRONICALLY MORPHINIZED RATS, Biochemistry and molecular biology international, 36(1), 1995, pp. 13-19
Citations number
23
Categorie Soggetti
Biology
Journal title
Biochemistry and molecular biology international → ACNP
ISSN journal
10399712
Volume
36
Issue
1
Year of publication
1995
Pages
13 - 19
Database
ISI
SICI code
1039-9712(1995)36:1<13:EONADO>2.0.ZU;2-3
Abstract
Effect of novel aromatic GABA derivative (AFA) on lipid peroxidation ( LP) was studied in the male rats of the Wistar strain. The morphine-re ceived animals had the higher level of LP in blood plasma, decreased l evel of total antioxidant activity, the increased rate of LP in the as corbate-induced system in liver homogenate. In the case of AFA adminis tration with morphine, all the above mentioned effects were almost wit hdrawn.