IMMUNODETECTION OF CLENBUTEROL IN THE HAIR OF CALVES

To validate the use of hair as a target for the detection of clenbuter ol, hair was collected from two groups of calves receiving clenbuterol at two doses of 10 (n = 3) and 100 mu g/kg (n = 3) for 10 days. Clenb uterol was extracted from hair by an immunochromatography procedure an d quantified by an enzyme immunoassay. Following the 10 mu g/kg dose, clenbuterol could be detected at day 20 after the last dose. However, at the 100 mu g/kg dose, clenbuterol could be found in hair 40 days af ter the last treatment. These data confirm that hair is a target of ch oice for the detection of clenbuterol as a drug residue when this drug is found undetectable in urine and tissue.