THE USE OF POLY R-478 AS A MARKER TO DETERMINE GASTRIC-EMPTYING AND INTESTINAL PROPULSIVE MOTILITY IN SUCKLING RATS

Authors
SHINOHARA H WILLIAMS C KOLDOVSKY O
Citation
H. Shinohara et al., THE USE OF POLY R-478 AS A MARKER TO DETERMINE GASTRIC-EMPTYING AND INTESTINAL PROPULSIVE MOTILITY IN SUCKLING RATS, Physiological Research, 44(5), 1995, pp. 281-286
Citations number
23
Categorie Soggetti
Physiology
Journal title
Physiological Research → ACNP
ISSN journal
08628408
Volume
44
Issue
5
Year of publication
1995
Pages
281 - 286
Database
ISI
SICI code
0862-8408(1995)44:5<281:TUOPRA>2.0.ZU;2-P
Abstract
During our studies on gastrointestinal motility in suckling rats using Cr-51 or Cr-51-EDTA as markers, we noticed that these markers - in co ntrast to studies in adult rats - ''adhered'' to the gastrointestinal wall of sucklings. We therefore decided to test the use of another non -absorbable marker Poly R-478 (an acetylated anthrapyridone chromophor e linked to an polyamino-ethylene-sodium ethylene sulfonate copolymer backbone developed by the Dynapol Corporation (Pale Alto, CA). This ne w method has appeared to be useful.