9-(beta-D-Xylofuranosyl)adenine and 9-(alpha-L-arabinofuranosyl)adenin
e have been modified to give a series of gr-amino-substituted nucleosi
des. Convenient methods of halogenation of these nucleosides and react
ions of 8-halogenated nucleosides with various amines are described. N
o significant cytotoxic or antiviral activity was found.