ROLE OF PREOPERATIVE AND POSTOPERATIVE SENSORIMOTOR TRAINING ON RESTORATION OF THE EQUILIBRIUM BEHAVIOR IN ADULT MICE FOLLOWING CEREBELLECTOMY

The equilibrium behavior of cerebellectomized C57/BL6 adult mice was s tudied on a rota rod rotating at 20 revolutions per minute and the inf luence of preoperative or/and postoperative training on restoration of equilibrium capabilities investigated. The duration of the preoperati ve training was either short (1 day) or long (7 days). The postoperati ve training began either the day after cerebellectomy or was delayed b y 7 days. The results demonstrate that postoperative training was effi cient in restoring the equilibrium behavior in all cases, except for t he animals which were trained for a long period (7 days) before the le sion. Preoperative training was also efficient providing it was long e nough (7 days), except for the animals which postoperative training be gan the day after cerebellectomy. It can be stated that both preoperat ive and postoperative trainings influence the restoration of the equil ibrium following a cerebellectomy and that, in some instances, preoper ative training can be as efficient as postoperative. (C) 1995 Academic Press, Inc.