Dj. Fletcher et al., IMPROVED METHOD FOR COMPUTATION OF POTENTIALS IN A REALISTIC HEAD SHAPE MODEL, IEEE transactions on biomedical engineering, 42(11), 1995, pp. 1094-1104
The Lead Field Analysis (LFA) algorithm, a new computational technique
for the calculation of potentials on the surface of a realistic head
shaped volume conductor model based on the Boundary Element Method and
the Reciprocity Theorem, is presented. The new algorithm, in comparis
on to the Standard Boundary Element Method, offers improved computatio
nal efficiency and lower storage requirements. It also yields more acc
urate surface potential results in the face of varying dipole source l
ocations for a head shape Boundary Element model with a given number o
f nodes. Additionally, the algorithm results in quasi-analytic express
ions of the derivatives of the surface potential with respect to the l
ocation of the sources, allowing the use of optimization techniques wi
th better convergence properties. A set of simulations demonstrating t
he increased robustness of the LFA Algorithm in the face of varying di
pole source parameters is also described.