Male rabbits that had recovered from myxomatosis transmitted to their
offspring some factor that increased by 22% the offspring's probabilit
y of survival to myxoma virus challenge. The degree of protection tran
smitted differed between sires challenged with different myxoma strain
s and between sires challenged with myxoma virus and those challenged
with Shope's fibroma virus (SFV). We suggest that future tests of the
resistance of wild rabbits should be designed to minimise or eliminate
the sire effect.